POLY (LACTIDE-CO-GLYCOLIDE) NANOFIBERS COATED WITH COLLAGEN AND NANO-HYDROXYAPATITE FOR BONE TISSUE ENGINEERING

Introduction 
Procedures for reconstruction surgery and organ transplantation improve the quality of life, and in some cases save life. However they are accompanied with various complications. In most cases these procedures require either organ donation from a donor individual or tissue transplantation from a second surgical site 1. Autografts exhibit the distinct advantage of histocompatibility without the risks of disease transfer and are still the gold standard for bone repair 2. The major problem with allograft and xenograft organ transplantation is that there exists a drastic threat of disease transmission and immune responses, which can lead to the graft failure. With the limited availability of donor organs, the science of tissue engineering has Nanofibers, collagen and nano-HA for bone tissue engineering Tavakoli-Darestani et al.